Publications
Peer Reviewed
Topical Administration of Novel FKBP12 Ligand MP-004 Improves Retinal Function and Structure in Retinitis Pigmentosa Models.
IOVS-Investigative Ophthalmology & Visual Science
03/2025
Novel FKBP prolyl isomerase 1A (FKBP12) ligand promotes functional improvement in SOD1G93A amyotrophic lateral sclerosis (ALS) mice.
British Journal of Pharmacology
02/2025
Pharmacokinetic Evaluation of New Drugs Using a Multi-Labelling Approach and PET Imaging: Application to a Drug Candidate with Potential Application in Neuromuscular Disorders.
Biomedicines
01/2023
Discovery of a novel family of FKBP12 “reshapers” and their use as calcium modulators in skeletal muscle under nitro-oxidative stress.
European Journal of Medicinal Chemistry.
01/2021
A Novel Class of FKBP12 Ligands Rescues Premature Aging Phenotypes Associated with Myotonic Dystrophy Type 1.
Cells
11/2024
Pre-Prints
Topical administration of novel FKBP12 ligand MP-004 improves retinal function and structure in retinitis pigmentosa models.
BioRxiv
10/2024
Disrupting the Feed-Forward Cycle of RyR1 Ca2+ Leak and Oxidative Stress Mitigates Doxorubicin-Induced Skeletal Myopathy.
BioRxiv
11/2025
Assessment of the pharmacological and safety profile of the small molecule MP-004 after topical eye drops administration.
BioRxiv
10/2025